Grand Theft Auto: Vice Strips returned the ability to use drugs. Mikhael can purchase drugs on Antoni's place for $50 after the mission Antoni's Drug Mart, where the drugs are introduced during that mission. Drugs are first debuted in GTA: Chinatown Wars.
There are 8 drugs that players can buy:
- Magic mushrooms
Each drug has different side effects to the player when consumed. For example, consuming weeds will cause Mikhael to get high and the camera will wobble around, causing the player difficult to be controlled. During the side effects, Mikhael will not able to shoot or kill people, everything will be in slow motion. He will also unable to sprint, and his jumps have no height. The player might also lose health, and might be wasted if the health is 10 percent or below.
- The mission might fail if player consumes drugs. However, it is rare.
- If player consumes more drugs, Mikhael will be transported at random places in Vice City. He can also be transported to Blue Hell, but it is also rare.
- In the Beta version, the player can store drugs, however, it was scrapped in the final version.